Dublin James Wahlberg is Maurice in The Van Buren Boys (Season 8 - Episode 14).

Dwayne Kennedy is Frank in The Stranded (Season 3 Episode 10).

Dyana Ortelli is Lupe, the Chambermaid in The Trip (Season 4 Episode 1).

Dylan Tays is Nicki in The Calzone (Season 7 Episode 19).

Eamonn Roche is the waiter in The Pie (Season 5 - Episode 15).

Earl Boen is Manya's eulogist in The Pony Remark (Season 2 Episode 2).

Earl Schuman is Izzy Mandelbaum Sr. in The English Patient (Season 8 - Episode 17).

Ed O'Ross is a police officer in The Engagement (Season 7 - Episode 1).

Eddie Allen is Doctor in The Fatigues (Season 8 Episode 6).

Edgar Small is Sid Luckman in The English Patient (Season 8 Episode 17).

Edie McClurg is Mrs. Oliver in The Old Man (Season 4 - Episode 18).

Edith Fields is Mrs. Payton in The Doorman (Season 6 Episode 18).

Edward Penn is Owen March in The Alternate Side (Season 3 Episode 11).

Edward Winter is Mr. Stevenson in The Beard (Season 6 Episode 16).

Elan Carter is Receptionist in The Jimmy (Season 6 Episode 19).

Elayn J. Taylor is book fan in The Muffin Tops (Season 8 - Episode 21).

Elena Wohl is Sandi Robbins (Elaine) in The Pilot (Season 4 Episode 23).

The elevator man appears in Male Unbonding (Season 1 Episode 4).

Elina Löwensohn is Katya in The Gymnast (Season 6 Episode 6).

Elizabeth Barrington is Mom in The Yada Yada (Season 8 - Episode 19).

Elizabeth Dennehy is Alison in The Handicap Spot (Season 4 Episode 22).

Elizabeth Morehead is Noel in The Pez Dispenser (Season 3 Episode 14).

Elizabeth Sjoli is the girl that meets George Costanza wearing a toupee in Monk's in The Scofflaw (Season 6 Episode 13).

Ella Joyce is Dean Jones in The Voice (Season 9 - Episode 2).

Ellen Albertini Dow is Peterman's momma in The Secret Code (Season 7 Episode 7).

Ellen Ratner is Ellen in The Stranded (Season 3 - Episode 10).

Elliott Reid is the Mr. Armstrong in The Letter (Season 3 Episode 21).